Oligometastatic Disease, SBRT, Immunotherapy, Genomics

Oligometastatic disease is a unique stage of cancer. Oligometastatic disease describes a limited spread of cancer to a few distant sites in the body. It holds significant importance in the world of oncology and challenges the traditional notion that advanced cancer is untreatable. Oligometastasis provides an opportunity for targeted intervention to prolong and improve the quality of life for patients.

“Oligometastasis is an emerging concept that is changing the landscape of cancer treatment,” says Dr. Sridhar PS. “By identifying and treating these isolated metastases, it’s possible to extend life and achieve remission.”

Dr. Sridhar PS, a renowned CyberKnife specialist in India, plays a pivotal role for those on their cancer journey. His expertise in utilizing cutting-edge technology ensures precise and effective treatment for oligometastatic disease.

Let’s delve deeper into how oligometastatic disease challenges traditional cancer treatment paradigms. Let’s understand the exciting possibilities on the horizon.

Oligometastatic Disease – How It Challenges Traditional Cancer Treatment Paradigms

Oligometastatic disease defies the idea that advanced cancer can’t be treated. Instead of giving up, it focuses on isolated metastases, aiming to remove or control them. This approach can extend life and improve outcomes.

“Early detection and management are crucial in oligometastatic disease,” says Dr. Sridhar PS. “Detecting these limited metastases early on allows for targeted treatment.”

With Dr. Sridhar PS, patients seeking advanced cancer treatment can benefit from CyberKnife in India and Kenya. He is at the forefront of this change, using cutting-edge technology for precise and effective treatment.

Don’t lose hope if you or a loved one faces this challenge. Consult Dr. Sridhar PS to explore tailored treatment options and enhance your chances of a better outcome.

Treating Oligometastatic Disease

Effective management strategies, including treatments like SBRT, Immunotherapy, and Genomics, can be employed to control or eliminate these isolated lesions. Early intervention in oligometastatic disease can lead to better outcomes, potentially extending life and improving the quality of life for patients.

Please visit Dr. Sridhar, an expert radiation oncologist in India, for early detection and successful management.

Continue reading to learn about sophisticated treatment options like SBRT, Immunotherapy, and

Genomics.

1.   Precision Strikes With SBRT (Stereotactic Body Radiation Therapy)

SBRT is an advanced cancer treatment that delivers highly precise, intense doses of radiation to tumors. It’s like using a laser beam to target cancer cells while minimizing damage to surrounding healthy tissue. Cancer experts often use SBRT for small, isolated tumors, and it requires just a few sessions.

While SBRT has advantages, it might only suit some cancers or situations. Dr. Sridhar PS can guide you to see if SBRT is right for you.

The key differences between SBRT and conventional radiation therapy are:

1.Dose Precision:

• SBRT delivers a very high radiation dose with pinpoint accuracy in fewer sessions, often in just a few days.
• Conventional radiation therapy uses lower doses over more sessions, often over several weeks.

2.Treatment Duration:

• SBRT typically involves a shorter treatment course, often completed in just a few sessions.
• Conventional radiation therapy extends over several weeks with daily treatments.

3.Targeted Approach:

• SBRT precisely targets the tumor while sparing nearby healthy tissue.
• Conventional radiation may affect a larger area, impacting healthy cells.

4.Suitability:

• SBRT is suitable for complex or hard-to-reach tumors requiring high precision.
• Conventional radiation therapy is used for various cancer types.

5.Effects:

• SBRT may have fewer side effects due to its focused nature.
• Conventional radiation therapy might lead to more generalized side effects.

The SBRT treatment cost in India may range from INR 1,00,000 to INR 4,00,000 or more per session. Please speak with Dr. Sridhar PS for an accurate estimate based on your case and treatment plan. He is the go-to doctor for people seeking IGRT and IMRT treatment in India.

2.    Revolutionizing Cancer Treatment With Immunotherapy

Cancer immunotherapy works by boosting the body’s immune system to fight cancer. It helps the immune cells recognize and attack cancer cells more effectively. Immunotherapy has led to remarkable success stories where patients with advanced cancer achieved remission or long-term control of their disease. These stories offer hope and showcase the potential of immunotherapy in cancer treatment.

Immunotherapy includes various methods, like:

• Checkpoint inhibitors that release brakes on immune cells
• CAR-T cell therapy modifies immune cells to target cancer.

These treatments help the immune system become a better cancer fighter.

Immunotherapy doctor in India, Dr. Sridhar PS, employs immunotherapy with traditional treatments for oligometastatic disease. When used together, they can improve outcomes by targeting cancer in different ways.

Genomics: The Personalized Approach

Genomics plays a significant role in understanding cancer. The aim is to delve deep into the genetic information of cancer cells. It helps medical experts unravel the molecular intricacies of cancer to uncover how and why it develops and spreads.

“Genomics helps us identify the specific genetic alterations that drive cancer growth,” explains Dr. Sridhar PS. “By decoding these genetic changes, we can gain valuable insights into each patient’s cancer at a molecular level. This information aids in tailoring precise and personalized treatment strategies. It improves the chances of successful cancer management and treatment outcomes.”

Consult with Dr. Sridhar PS to explore how genomics can benefit your cancer treatment. Dr. Sridhar is a highly respected cancer specialist. He is known for CyberKnife in Bangalore and various cancer treatments, including radiation therapy in India.

Understanding your unique genomic profile may lead to more effective therapies and better outcomes.

Conclusion

In the ever-evolving landscape of cancer care, the future is illuminated by the promise of precision medicine. With cutting-edge technologies like CyberKnife treatment in India, patients can now access targeted, tailored therapies. These advanced therapies can potentially transform how we combat this complex disease.

By embracing precision medicine, patients can embark on a journey towards:

• More effective treatments
• Fewer side effects
• Improved outcomes

The key to unlocking the future of cancer care lies in the hands of experts like Dr. Sridhar PS, who collaborate to explore groundbreaking options.

Do not delay in your journey toward innovative treatment. Schedule a consultation with Dr. Sridhar at the earliest.

CASE STUDY Patient Profile

Name: Das

Age: 70 years

Symptoms

Das presented with a history of the following symptoms over 2 months in 2017:

• Persistent headaches accompanied by vomiting
• Seizures
• Balance issues

Diagnostic Tests Performed

A comprehensive set of diagnostic tests and evaluations were carried out, including:

• Surgical Biopsy: Dr. Sridhar PS conducted a surgical biopsy, where he surgically removed a small tissue sample from the affected area. This procedure allows for a precise diagnosis by examining the tissue under a microscope.

• Histopathological Examination: Dr. Sridhar PS carefully examined the tissue sample through histopathological examination. This microscopic analysis provided insights into the nature of the tissue, helping confirm the presence of cancer and its characteristics.

• Molecular Testing for ALK, EGFR, and PDL1 Mutations: Dr. Sridhar PS oversaw molecular testing, which involved analyzing the genetic composition of cancer cells. This advanced testing identified specific mutations in genes like ALK, EGFR, and PDL1*. It aided in the selection of tailored treatment strategies.

*ALK: Anaplastic Lymphoma Kinase

*EGFR: Epidermal Growth Factor Receptor

*PDL1: Programmed Death-Ligand 1

• FDG PET CT* Scan: Dr. Sridhar PS interpreted the results of the FDG PET CT scan, a diagnostic imaging procedure. By using a radioactive glucose solution, this scan highlighted areas of increased metabolic activity. It aided him in the detection of cancerous lesions and guiding treatment decisions.

* FDG PET CT: Fluorodeoxyglucose Positron Emission Tomography with Computed Tomography

• Contrast-Enhanced MRI* of the Brain: Dr. Sridhar PS analyzed the results of the contrast-enhanced MRI of the brain. This MRI, using a contrast agent, produced detailed images, enabling the precise identification of brain tumors, metastases, or other abnormalities in the patient’s brain.

* MRI (Magnetic Resonance Imaging

Diagnosis

The combined results of these tests led to the diagnosis of Adenocarcinoma Lung With Brain and Adrenal Metastases

Treatment

To address Das’s condition, a multi-modal treatment approach was implemented:

Dr. Sridhar PS administered SBRT (Stereotactic Body Radiation Therapy) with a dose of 30 Gy in 5 fractions. This precise radiation therapy targeted the primary lung lesions and metastatic lesions in the brain and left adrenal gland.

Additionally, the patient received chemotherapy consisting of Paclitaxel at a dosage of 50 mg/m2 and carboplatin at an AUC*2. This chemotherapy regimen was completed over 6 cycles.

Post-Treatment Guidelines

Following treatment, the patient was advised to adhere to specific post-treatment guidelines:

• Regular clinical examinations were recommended to monitor the patient’s progress and overall health.
• Periodic FDG PET CT scans were scheduled to assess the effectiveness of the treatment and check for any signs of cancer recurrence.
• Contrast-enhanced MRI of the brain was included in the follow-up protocol to ensure any changes or developments in the brain were promptly detected and addressed.

Patient Feedback for Radiation Oncologist – Dr. Sridhar PS:

Das expressed gratitude and satisfaction with the treatment and care provided by Dr. Sridhar PS. The compassionate and expert guidance throughout the treatment journey played a significant role in Das’s positive outlook and improved health.

FAQ

Q. What is oligometastatic disease?

Oligometastatic disease is a cancer that has spread to only a few distant sites.

Q. How is oligometastatic disease different from advanced cancer?

Oligometastatic disease has fewer isolated metastases, while advanced cancer has more widespread metastases.

Q. Can oligometastatic disease be treated?

It can be treated with targeted therapies like SBRT or surgery that aim for long-term control or even remission. In some cases, oligometastatic disease can be cured, especially when all metastases are treated successfully.